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Laser Ablation Inductively Coupled Plasma Mass Spectrometry Method
Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) is an analytical technique that combines the principles of laser ablation and inductively coupled plasma mass spectrometry (ICP-MS) to determine the elemental composition of solid samples.
In LA-ICP-MS, a pulsed laser beam is focused onto a sample surface, vaporizing and ionizing a small amount of material. The resulting plasma is then introduced into the ICP-MS, where it is further ionized and separated by mass-to-charge ratio. The abundance of each element in the sample can then be quantified by measuring the intensity of the corresponding ion signal.
Advantages of LA-ICP-MS
- High spatial resolution: LA-ICP-MS allows for the analysis of very small areas, down to a few micrometers in diameter.
- High sensitivity: LA-ICP-MS can detect elements at very low concentrations, often in the parts per billion range.
- Versatility: LA-ICP-MS can be used to analyze a wide variety of solid samples, including metals, ceramics, and geological materials.
- Non-destructive: LA-ICP-MS is a non-destructive analytical technique, meaning that the sample does not need to be destroyed during the analysis.
Applications of LA-ICP-MS
- Geochemistry: LA-ICP-MS is used to study the elemental composition of rocks, minerals, and soils.
- Materials science: LA-ICP-MS is used to characterize the elemental composition of materials, such as metals, ceramics, and semiconductors.
- Environmental science: LA-ICP-MS is used to analyze the elemental composition of environmental samples, such as air, water, and soil.
- Biological science: LA-ICP-MS is used to study the elemental composition of biological samples, such as cells and tissues.
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